Product ID:TRIS, ULTROL GRADE, 648311
MSDS Date:11/11/1998
FSC:6505
NIIN:00N092495
Status Code:A
MSDS Number: CJSPM

Emergency Phone: 202-783-7616 (INTERNATL)

Info Phone: 800-854-3417; 619-450-5558

Cage: 29089

Telephone: 619-450-5558; 800-854-3417

Cage: 29089

TRIS(HYDROXYMETHYL)AMINOMETHANE

CAS: 77-86-1

RTECS: TY2900000

LD50 LC50 Mixture:LD50:(ORAL,RAT) 5900 MG/KG & TOX INFO
Routes of Entry: Inhalation:YES Skin:YES Ingestion:YES
Reports of Carcinogenicity:NTP:NO IARC:NO OSHA:NO
Health Hazards Acute and Chronic:MAY BE HARMFUL BY INGESTION,
INHALATION OR ABSORPTION THROUGH SKIN. MATERIAL MAY CAUSE
IRRITATION TO THE EYES, SKIN, MUCOUS MEMBRANES, AND THE UPPER
RESPIRATORY TRACT.
Effects of Overexposure:SEE HEALTH HAZARDS.

First Aid:SKIN: WASH WITH COPIOUS AMOUNTS OF WATER FOR AT LEAST 15
MINUTES. REMOVE CONTAMINATED CLOTHING AND SHOES AND WASH BEFORE
WEARING. CONSULT MD. EYES: FLUSH WITH COPIOUS AMOUNTS OF WATER FOR
AT LEAST 15 MINUTES. ASSURE ADEQUATE FLUSHING BY SEPARATING
EYELIDS WITH FINGERS. CONSULT MD. INHALATION: REMOVE TO FRESH AIR
AND MONITOR BREATHING. IF BREATHING BECOMES DIFFICULT, GIVE OXYGEN
AND CONSULT MD. IF BREATHING STOPS, GIVE ARTIFICIAL RESPIRATION
AND CONSULT MD. INGESTION: WASH MOUTH OUT WITH WATER AND CONSULT
LOCAL POISON CENTER AND MD.

Extinguishing Media:DRY CHEMICAL POWDER, CARBON DIOXIDE, WATER SPRAY,
ALCOHOL OR POLYMER FOAM.
Fire Fighting Procedures:USE NIOSH APPROVED SCBA AND FULL PROTECTIVE
EQUIPMENT .
Unusual Fire/Explosion Hazard:UPON THERMAL DECOMPOSITION, IT MAY EMIT
TOXIC GASES.

Spill Release Procedures:EVACUATE AREA. WEAR A NIOSH APPROVED
RESPIRATOR, CHEMICAL SAFETY GOGGLES, RUBBER BOOTS AND HEAVY RUBBER
GLOVES. SWEEP UP AND PLACE IN A SUITABLE CONTAINER. AVOID RAISING
DUST. HOLD FOR APPROPRIATE DIS POSAL. WASH SPILL SITE AND VENTILATE
AREA AFTER MATERIAL PICKUP IS COMPLETE.

Handling and Storage Precautions:STORE IN A TIGHTLY CLOSED CONTAINER IN
A COOL, DRY PLACE (+20C). MATERIAL IS AN IRRITANT. AVOID CONTACT
WITH MATERIAL. AVOID PROLONGED OR REPEATED EXPOSURE. DO NOT BREATHE
DUST. AVOID CONTACT WITH SKI N AND EYES.
Other Precautions:IN CASE OF ACCIDENT OR IF YOU FEEL UNWELL, SEEK
MEDICAL ADVICE IMMEDIATELY. MATERIAL SHOULD ONLY BE HANDLED BY
QUALIFIED, EXPERIENCED PROFESSIONALS.

Respiratory Protection:USE A NIOSH APPROVED RESPIRATOR.
Ventilation:HANDLE IN A CHEMICAL FUME HOOD WITH ADEQUATE VENTILATION.
Protective Gloves:CHEMICAL RESISTANT GLOVES.
Eye Protection:ANSI APPROVED CHEMICAL WORKERS GOGGLES & FULL LENGTH
FACESHIELD .
Other Protective Equipment:ANSI APPROVED EYE WASH & DELUGE SHOWER .
WEAR SUITABLE PROTECTIVE CLOTHING.
Work Hygienic Practices:WASH THOROUGHLY AFTER HANDLING MATERIAL.
Supplemental Safety and Health
MFR'S INFO: MFR'S FAX #: (619) 452-3552; MFR'S INFO ON INGS: MOLECULAR
WEIGHT: 121.1. MOLECULAR FORMULA: C*4H*11NO*3.

Melt/Freeze Pt:>171.1C, 340.2F
M.P/F.P Text:171.2-172.3C
Solubility in Water:SOLUBLE
Appearance and Odor:WHITE SOLID.

Stability Indicator/Materials to Avoid:YES
AVOID CONTACT WITH BASES AND OXIDIZING AGENTS.
Stability Condition to Avoid:STABLE UNDER NORMAL HANDLING PROCEDURES.
Hazardous Decomposition Products:UPON THERMAL DECOMPOSITION, MAY EMIT
TOXIC GASES INCLUDING CARBON MONOXIDE, CARBON DIOXIDE AND NITROGEN
OXIDES.

Waste Disposal Methods:COUNTRY, FEDERAL, STATE & LOCAL REGS ARE VARIED
& CHANGE FREQUENTLY. FOR THIS REASON, MFR RECOMMENDS THAT YOU CONT
YOUR LOCAL DEPARTMENT OF HEALTH SERVICES FOR INFO ON THE DISPOSAL
OF THIS PROD/ARRANG E FOR DISPOSAL BY A LICENSED DISPOSAL COMPANY.
DISPOSE OF IN ACCORDANCE WITH FEDERAL, STATE AND LOCA L REGULATIONS
.

Toxicological Information:TOX DATA & REFERENCES: LD50:(ORAL,RAT) 5900
MG/KG 1971. "BOLLETTINO CHIMICO FARMACEUTICO". 110, 653.
LD50:(IVN,RAT) 1800 MG/KG 1990. "DRUGS IN JAPAN (ETHICAL DRUGS)".
-, 419. LD50:(IVN,MUS) 1210 MG/M3 1966. "ACTA BIOLOGICA ET MEDICA
GERMANICA". 17, 217. REFER TO THE REGISTRY OF TOXIC EFFECTS OF
CHEMICAL SUBSTANCES (RTECS) FOR A DEFINITION OF ABBREVIATIONS USED
IN TEXT AND FOR ADDITIONAL INFORMATIO N. THIS REPORT CONTAINS ONLY
SELECTED INFORMATION FROM RTECS.

Disclaimer (provided with this information by the compiling agencies):
This information is formulated for use by elements of the Department
of Defense. The United States of America in no manner whatsoever,
expressly or implied, warrants this information to be accurate and
disclaims all liability for its use. Any person utilizing this
document should seek competent professional advice to verify and
assume responsibility for the suitability of this information to their
particular situation.

Ecological:NO INFORMATION AVAILABLE.

Transport Information:UN NUMBER: N/A. PROPER SHIPPING NAME: N/A. IATA
CLASS: N/A. IATA PACKING GROUP: N/A.

Federal Regulatory Information:REGULATORY INFORMATION: XI. RISK
PHRASES: R36/37/38: IRRITATING TO EYES, RESPIRATORY SYSTEM AND
SKIN. SAFETY PHRASES: S22: DO NOT BREATHE DUST. S24/25: AVOID
CONTACT WITH SKIN AND EYES. S26: IN CASE O F CONTACT WITH EYES,
RINSE IMMEDIATELY WITH PLENTY OF WATER AND SEEK MEDICAL ADVICE.
S36/37/39: WEAR SUITABLE PROTECTIVE CLOTHING, GLOVES AND EYE/FACE
PROTECTION. S45:IN CASE OF ACCIDENT OR IF YOU FEE L UNWELL, SEEK
MEDICAL ADVICE IMMEDIATELY.
State Regulatory Information: